WallStSmart

Iovance Biotherapeutics Inc (IOVA)vsRegeneron Pharmaceuticals Inc (REGN)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Regeneron Pharmaceuticals Inc generates 5124% more annual revenue ($14.92B vs $285.61M). REGN leads profitability with a 29.6% profit margin vs -123.9%. REGN earns a higher WallStSmart Score of 64/100 (C+).

IOVA

Avoid

34

out of 100

Grade: F

Growth: 6.3Profit: 2.0Value: 5.0Quality: 6.5
Piotroski: 3/9Altman Z: -3.03

REGN

Buy

64

out of 100

Grade: C+

Growth: 5.3Profit: 7.5Value: 8.0Quality: 8.5
Piotroski: 2/9Altman Z: 4.44
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

Intrinsic value data unavailable for IOVA.

REGNUndervalued (+53.0%)

Margin of Safety

+53.0%

Fair Value

$1350.89

Current Price

$635.45

$715.44 discount

UndervaluedFair: $1350.89Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

IOVA3 strengths · Avg: 9.3/10
Revenue GrowthGrowth
44.8%10/10

Revenue surging 44.8% year-over-year

Debt/EquityHealth
0.0610/10

Conservative balance sheet, low leverage

Price/BookValuation
2.3x8/10

Reasonable price relative to book value

REGN6 strengths · Avg: 9.0/10
Debt/EquityHealth
0.0910/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
4.4410/10

Safe zone — low bankruptcy risk

Market CapQuality
$63.21B9/10

Large-cap with strong market position

Profit MarginProfitability
29.6%9/10

Keeps 30 of every $100 in revenue as profit

P/E RatioValuation
14.7x8/10

Attractively priced relative to earnings

Price/BookValuation
2.1x8/10

Reasonable price relative to book value

Areas to Watch

IOVA4 concerns · Avg: 3.0/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$1.84B3/10

Smaller company, higher risk/reward

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Return on EquityProfitability
-47.5%2/10

ROE of -47.5% — below average capital efficiency

REGN2 concerns · Avg: 2.5/10
Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

EPS GrowthGrowth
-7.2%2/10

Earnings declined 7.2%

Comparative Analysis Report

WallStSmart Research

Bull Case : IOVA

The strongest argument for IOVA centers on Revenue Growth, Debt/Equity, Price/Book. Revenue growth of 44.8% demonstrates continued momentum.

Bull Case : REGN

The strongest argument for REGN centers on Debt/Equity, Altman Z-Score, Market Cap. Profitability is solid with margins at 29.6% and operating margin at 20.7%. Revenue growth of 19.0% demonstrates continued momentum.

Bear Case : IOVA

The primary concerns for IOVA are EPS Growth, Market Cap, Piotroski F-Score.

Bear Case : REGN

The primary concerns for REGN are Piotroski F-Score, EPS Growth.

Key Dynamics to Monitor

IOVA profiles as a hypergrowth stock while REGN is a growth play — different risk/reward profiles.

IOVA carries more volatility with a beta of 0.70 — expect wider price swings.

IOVA is growing revenue faster at 44.8% — sustainability is the question.

REGN generates stronger free cash flow (848M), providing more financial flexibility.

Bottom Line

REGN scores higher overall (64/100 vs 34/100), backed by strong 29.6% margins and 19.0% revenue growth. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Iovance Biotherapeutics Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Iovance Biotherapeutics, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing cancer immunotherapy products to harness the power of a patient's immune system to eradicate cancer cells. The company is headquartered in San Carlos, California.

Regeneron Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Regeneron Pharmaceuticals, Inc. is an American biotechnology company headquartered in Westchester County, New York. Originally focused on neurotrophic factors and their regenerative capabilities, giving rise to its name, the company then branched out into the study of both cytokine and tyrosine kinase receptors.

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