WallStSmart

Innoviva Inc (INVA)vsVertex Pharmaceuticals Inc (VRTX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Vertex Pharmaceuticals Inc generates 2761% more annual revenue ($12.59B vs $440.00M). INVA leads profitability with a 81.2% profit margin vs 35.0%. INVA appears more attractively valued with a PEG of 0.26. INVA earns a higher WallStSmart Score of 85/100 (A-).

INVA

Exceptional Buy

85

out of 100

Grade: A-

Growth: 8.0Profit: 9.0Value: 8.3Quality: 8.5
Piotroski: 3/9Altman Z: 3.20

VRTX

Buy

64

out of 100

Grade: C+

Growth: 6.7Profit: 9.0Value: 6.7Quality: 8.5
Piotroski: 3/9Altman Z: 3.61
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

Intrinsic value data unavailable for INVA.

VRTXUndervalued (+46.5%)

Margin of Safety

+46.5%

Fair Value

$963.47

Current Price

$515.44

$448.03 discount

UndervaluedFair: $963.47Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

INVA6 strengths · Avg: 10.0/10
PEG RatioValuation
0.2610/10

Growing faster than its price suggests

P/E RatioValuation
4.9x10/10

Attractively priced relative to earnings

Price/BookValuation
1.2x10/10

Reasonable price relative to book value

Return on EquityProfitability
37.6%10/10

Every $100 of equity generates 38 in profit

Profit MarginProfitability
81.2%10/10

Keeps 81 of every $100 in revenue as profit

Operating MarginProfitability
43.3%10/10

Strong operational efficiency at 43.3%

VRTX6 strengths · Avg: 9.7/10
Profit MarginProfitability
35.0%10/10

Keeps 35 of every $100 in revenue as profit

Operating MarginProfitability
38.1%10/10

Strong operational efficiency at 38.1%

Debt/EquityHealth
0.1010/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
3.6110/10

Safe zone — low bankruptcy risk

Market CapQuality
$130.56B9/10

Large-cap with strong market position

Return on EquityProfitability
21.8%9/10

Every $100 of equity generates 22 in profit

Areas to Watch

INVA2 concerns · Avg: 3.0/10
Market CapQuality
$1.53B3/10

Smaller company, higher risk/reward

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

VRTX3 concerns · Avg: 3.7/10
PEG RatioValuation
1.894/10

Expensive relative to growth rate

P/E RatioValuation
30.0x4/10

Moderate valuation

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : INVA

The strongest argument for INVA centers on PEG Ratio, P/E Ratio, Price/Book. Profitability is solid with margins at 81.2% and operating margin at 43.3%. Revenue growth of 19.3% demonstrates continued momentum.

Bull Case : VRTX

The strongest argument for VRTX centers on Profit Margin, Operating Margin, Debt/Equity. Profitability is solid with margins at 35.0% and operating margin at 38.1%. Revenue growth of 12.5% demonstrates continued momentum.

Bear Case : INVA

The primary concerns for INVA are Market Cap, Piotroski F-Score.

Bear Case : VRTX

The primary concerns for VRTX are PEG Ratio, P/E Ratio, Piotroski F-Score.

Key Dynamics to Monitor

INVA profiles as a growth stock while VRTX is a mature play — different risk/reward profiles.

INVA carries more volatility with a beta of 0.33 — expect wider price swings.

INVA is growing revenue faster at 19.3% — sustainability is the question.

VRTX generates stronger free cash flow (1.0B), providing more financial flexibility.

Bottom Line

INVA scores higher overall (85/100 vs 64/100), backed by strong 81.2% margins and 19.3% revenue growth. VRTX offers better value entry with a 46.5% margin of safety. Both earn "Exceptional Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Innoviva Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Innoviva, Inc. is dedicated to the development and commercialization of pharmaceutical products. The company is headquartered in Burlingame, California.

Vertex Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Vertex Pharmaceuticals, Inc. is an American biopharmaceutical company based in Boston, Massachusetts.

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