WallStSmart

Immunocore Holdings Ltd (IMCR)vsVertex Pharmaceuticals Inc (VRTX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Vertex Pharmaceuticals Inc generates 2860% more annual revenue ($12.22B vs $412.81M). VRTX leads profitability with a 35.5% profit margin vs -6.7%. VRTX earns a higher WallStSmart Score of 68/100 (B-).

IMCR

Hold

42

out of 100

Grade: D

Growth: 8.7Profit: 3.0Value: 5.0Quality: 7.0
Piotroski: 4/9Altman Z: 0.36

VRTX

Strong Buy

68

out of 100

Grade: B-

Growth: 8.0Profit: 9.0Value: 6.7Quality: 8.5
Piotroski: 3/9Altman Z: 3.62
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

Intrinsic value data unavailable for IMCR.

VRTXUndervalued (+53.1%)

Margin of Safety

+53.1%

Fair Value

$952.53

Current Price

$446.83

$505.70 discount

UndervaluedFair: $952.53Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

IMCR2 strengths · Avg: 9.5/10
EPS GrowthGrowth
150.0%10/10

Earnings expanding 150.0% YoY

Debt/EquityHealth
0.119/10

Conservative balance sheet, low leverage

VRTX6 strengths · Avg: 9.7/10
Profit MarginProfitability
35.5%10/10

Keeps 36 of every $100 in revenue as profit

Operating MarginProfitability
38.1%10/10

Strong operational efficiency at 38.1%

EPS GrowthGrowth
61.4%10/10

Earnings expanding 61.4% YoY

Altman Z-ScoreHealth
3.6210/10

Safe zone — low bankruptcy risk

Market CapQuality
$107.89B9/10

Large-cap with strong market position

Return on EquityProfitability
22.4%9/10

Every $100 of equity generates 22 in profit

Areas to Watch

IMCR4 concerns · Avg: 2.3/10
Market CapQuality
$1.47B3/10

Smaller company, higher risk/reward

Return on EquityProfitability
-7.1%2/10

ROE of -7.1% — below average capital efficiency

Free Cash FlowQuality
$-15.53M2/10

Negative free cash flow — burning cash

Altman Z-ScoreHealth
0.362/10

Distress zone — elevated risk

VRTX3 concerns · Avg: 3.7/10
PEG RatioValuation
1.654/10

Expensive relative to growth rate

P/E RatioValuation
25.3x4/10

Moderate valuation

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : IMCR

The strongest argument for IMCR centers on EPS Growth, Debt/Equity. Revenue growth of 13.6% demonstrates continued momentum.

Bull Case : VRTX

The strongest argument for VRTX centers on Profit Margin, Operating Margin, EPS Growth. Profitability is solid with margins at 35.5% and operating margin at 38.1%.

Bear Case : IMCR

The primary concerns for IMCR are Market Cap, Return on Equity, Free Cash Flow.

Bear Case : VRTX

The primary concerns for VRTX are PEG Ratio, P/E Ratio, Piotroski F-Score.

Key Dynamics to Monitor

IMCR profiles as a turnaround stock while VRTX is a mature play — different risk/reward profiles.

IMCR carries more volatility with a beta of 0.75 — expect wider price swings.

IMCR is growing revenue faster at 13.6% — sustainability is the question.

VRTX generates stronger free cash flow (1.3B), providing more financial flexibility.

Bottom Line

VRTX scores higher overall (68/100 vs 42/100), backed by strong 35.5% margins. Both earn "Strong Buy" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Immunocore Holdings Ltd

HEALTHCARE · BIOTECHNOLOGY · USA

Immunocore Holdings Limited, an advanced stage biotechnology company, develops immunotherapies for the treatment of cancer, infectious and autoimmune diseases. The company is headquartered in Abingdon, the United Kingdom.

Vertex Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Vertex Pharmaceuticals, Inc. is an American biopharmaceutical company based in Boston, Massachusetts.

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