WallStSmart

Illumina Inc (ILMN)vsNatera Inc (NTRA)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Illumina Inc generates 66% more annual revenue ($4.49B vs $2.71B). ILMN leads profitability with a 18.3% profit margin vs -7.1%. ILMN earns a higher WallStSmart Score of 56/100 (C).

ILMN

Buy

56

out of 100

Grade: C

Growth: 3.3Profit: 8.5Value: 5.3Quality: 6.5
Piotroski: 6/9Altman Z: 1.88

NTRA

Avoid

31

out of 100

Grade: F

Growth: 8.0Profit: 2.0Value: 5.0Quality: 6.0
Piotroski: 3/9Altman Z: 0.82
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ILMNUndervalued (+58.4%)

Margin of Safety

+58.4%

Fair Value

$279.71

Current Price

$206.45

$73.26 discount

UndervaluedFair: $279.71Overvalued

Intrinsic value data unavailable for NTRA.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ILMN2 strengths · Avg: 8.5/10
Return on EquityProfitability
29.1%9/10

Every $100 of equity generates 29 in profit

Operating MarginProfitability
21.1%8/10

Strong operational efficiency at 21.1%

NTRA2 strengths · Avg: 9.5/10
Revenue GrowthGrowth
37.7%10/10

Revenue surging 37.7% year-over-year

Debt/EquityHealth
0.139/10

Conservative balance sheet, low leverage

Areas to Watch

ILMN4 concerns · Avg: 3.5/10
P/E RatioValuation
39.3x4/10

Premium valuation, high expectations priced in

Price/BookValuation
11.0x4/10

Trading at 11.0x book value

Altman Z-ScoreHealth
1.884/10

Grey zone — moderate risk

PEG RatioValuation
2.692/10

Expensive relative to growth rate

NTRA4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Price/BookValuation
25.9x2/10

Trading at 25.9x book value

Return on EquityProfitability
-10.6%2/10

ROE of -10.6% — below average capital efficiency

Comparative Analysis Report

WallStSmart Research

Bull Case : ILMN

The strongest argument for ILMN centers on Return on Equity, Operating Margin. Profitability is solid with margins at 18.3% and operating margin at 21.1%.

Bull Case : NTRA

The strongest argument for NTRA centers on Revenue Growth, Debt/Equity. Revenue growth of 37.7% demonstrates continued momentum.

Bear Case : ILMN

The primary concerns for ILMN are P/E Ratio, Price/Book, Altman Z-Score.

Bear Case : NTRA

The primary concerns for NTRA are EPS Growth, Piotroski F-Score, Price/Book.

Key Dynamics to Monitor

ILMN profiles as a mature stock while NTRA is a hypergrowth play — different risk/reward profiles.

NTRA carries more volatility with a beta of 1.53 — expect wider price swings.

NTRA is growing revenue faster at 37.7% — sustainability is the question.

ILMN generates stronger free cash flow (161M), providing more financial flexibility.

Bottom Line

ILMN scores higher overall (56/100 vs 31/100), backed by strong 18.3% margins. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Illumina Inc

HEALTHCARE · DIAGNOSTICS & RESEARCH · USA

Illumina, Inc. is an American company. Incorporated on April 1, 1998, Illumina develops, manufactures, and markets integrated systems for the analysis of genetic variation and biological function. The company provides a line of products and services that serves the sequencing, genotyping and gene expression, and proteomics markets. Its headquarters are located in San Diego, California.

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Natera Inc

HEALTHCARE · DIAGNOSTICS & RESEARCH · USA

Natera, Inc., a diagnostic company, develops and markets molecular testing services globally. The company is headquartered in San Carlos, California.

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