WallStSmart

CalciMedica, Inc. Common Stock (CALC)vsRegeneron Pharmaceuticals Inc (REGN)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

REGN leads profitability with a 29.6% profit margin vs 0.0%. REGN earns a higher WallStSmart Score of 64/100 (C+).

CALC

Avoid

19

out of 100

Grade: F

Growth: 4.3Profit: 3.0Value: 5.0Quality: 3.8
Piotroski: 1/9Altman Z: -25.47

REGN

Buy

64

out of 100

Grade: C+

Growth: 5.3Profit: 7.5Value: 8.0Quality: 8.5
Piotroski: 2/9Altman Z: 4.44
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

Intrinsic value data unavailable for CALC.

REGNUndervalued (+53.0%)

Margin of Safety

+53.0%

Fair Value

$1346.63

Current Price

$631.81

$714.82 discount

UndervaluedFair: $1346.63Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

CALC0 strengths · Avg: 0/10

No standout strengths identified

REGN6 strengths · Avg: 9.0/10
Debt/EquityHealth
0.0910/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
4.4410/10

Safe zone — low bankruptcy risk

Market CapQuality
$66.35B9/10

Large-cap with strong market position

Profit MarginProfitability
29.6%9/10

Keeps 30 of every $100 in revenue as profit

P/E RatioValuation
15.5x8/10

Attractively priced relative to earnings

Price/BookValuation
2.0x8/10

Reasonable price relative to book value

Areas to Watch

CALC4 concerns · Avg: 3.5/10
Revenue GrowthGrowth
0.0%4/10

0.0% revenue growth

EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$12.89M3/10

Smaller company, higher risk/reward

Profit MarginProfitability
0.0%3/10

0.0% margin — thin

REGN2 concerns · Avg: 2.5/10
Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

EPS GrowthGrowth
-7.2%2/10

Earnings declined 7.2%

Comparative Analysis Report

WallStSmart Research

Bull Case : CALC

CALC has a balanced fundamental profile.

Bull Case : REGN

The strongest argument for REGN centers on Debt/Equity, Altman Z-Score, Market Cap. Profitability is solid with margins at 29.6% and operating margin at 20.7%. Revenue growth of 19.0% demonstrates continued momentum.

Bear Case : CALC

The primary concerns for CALC are Revenue Growth, EPS Growth, Market Cap.

Bear Case : REGN

The primary concerns for REGN are Piotroski F-Score, EPS Growth.

Key Dynamics to Monitor

CALC profiles as a value stock while REGN is a growth play — different risk/reward profiles.

CALC carries more volatility with a beta of 1.24 — expect wider price swings.

REGN is growing revenue faster at 19.0% — sustainability is the question.

REGN generates stronger free cash flow (848M), providing more financial flexibility.

Bottom Line

REGN scores higher overall (64/100 vs 19/100), backed by strong 29.6% margins and 19.0% revenue growth. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

CalciMedica, Inc. Common Stock

HEALTHCARE · BIOTECHNOLOGY · USA

CalciMedica, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative therapies that modulate calcium-dependent pathways to address acute and chronic health issues. Its lead candidate, CM4620, targets severe muscle cramps in patients with sickle cell disease, highlighting the company's commitment to tackling critical unmet medical needs. With a proprietary technology platform and a well-defined pipeline of novel calcium modulators, CalciMedica is well-positioned for growth. The company is supported by a seasoned management team and strategic partnerships aimed at accelerating its clinical development, making it a noteworthy investment opportunity in the biopharmaceutical landscape.

Regeneron Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Regeneron Pharmaceuticals, Inc. is an American biotechnology company headquartered in Westchester County, New York. Originally focused on neurotrophic factors and their regenerative capabilities, giving rise to its name, the company then branched out into the study of both cytokine and tyrosine kinase receptors.

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