WallStSmart

Ascendis Pharma AS (ASND)vsRegeneron Pharmaceuticals Inc (REGN)

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Smart Verdict

WallStSmart Research — data-driven comparison

Regeneron Pharmaceuticals Inc generates 1623% more annual revenue ($14.92B vs $865.78M). ASND leads profitability with a 57.3% profit margin vs 29.6%. REGN trades at a lower P/E of 14.7x. REGN earns a higher WallStSmart Score of 64/100 (C+).

ASND

Buy

55

out of 100

Grade: C

Growth: 8.0Profit: 7.0Value: 5.3Quality: 3.0
Piotroski: 3/9Altman Z: -2.67

REGN

Buy

64

out of 100

Grade: C+

Growth: 5.3Profit: 7.5Value: 8.0Quality: 8.5
Piotroski: 2/9Altman Z: 4.44
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

Intrinsic value data unavailable for ASND.

REGNUndervalued (+53.0%)

Margin of Safety

+53.0%

Fair Value

$1350.89

Current Price

$635.45

$715.44 discount

UndervaluedFair: $1350.89Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ASND3 strengths · Avg: 10.0/10
Return on EquityProfitability
103.7%10/10

Every $100 of equity generates 104 in profit

Profit MarginProfitability
57.3%10/10

Keeps 57 of every $100 in revenue as profit

Revenue GrowthGrowth
144.3%10/10

Revenue surging 144.3% year-over-year

REGN6 strengths · Avg: 9.0/10
Debt/EquityHealth
0.0910/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
4.4410/10

Safe zone — low bankruptcy risk

Market CapQuality
$63.21B9/10

Large-cap with strong market position

Profit MarginProfitability
29.6%9/10

Keeps 30 of every $100 in revenue as profit

P/E RatioValuation
14.7x8/10

Attractively priced relative to earnings

Price/BookValuation
2.1x8/10

Reasonable price relative to book value

Areas to Watch

ASND4 concerns · Avg: 3.0/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Debt/EquityHealth
1.843/10

Elevated debt levels

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Price/BookValuation
23.3x2/10

Trading at 23.3x book value

REGN2 concerns · Avg: 2.5/10
Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

EPS GrowthGrowth
-7.2%2/10

Earnings declined 7.2%

Comparative Analysis Report

WallStSmart Research

Bull Case : ASND

The strongest argument for ASND centers on Return on Equity, Profit Margin, Revenue Growth. Profitability is solid with margins at 57.3% and operating margin at 10.1%. Revenue growth of 144.3% demonstrates continued momentum.

Bull Case : REGN

The strongest argument for REGN centers on Debt/Equity, Altman Z-Score, Market Cap. Profitability is solid with margins at 29.6% and operating margin at 20.7%. Revenue growth of 19.0% demonstrates continued momentum.

Bear Case : ASND

The primary concerns for ASND are EPS Growth, Debt/Equity, Piotroski F-Score. Debt-to-equity of 1.84 is elevated, increasing financial risk.

Bear Case : REGN

The primary concerns for REGN are Piotroski F-Score, EPS Growth.

Key Dynamics to Monitor

ASND carries more volatility with a beta of 0.48 — expect wider price swings.

ASND is growing revenue faster at 144.3% — sustainability is the question.

REGN generates stronger free cash flow (848M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

REGN scores higher overall (64/100 vs 55/100), backed by strong 29.6% margins and 19.0% revenue growth. Both earn "Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Ascendis Pharma AS

HEALTHCARE · BIOTECHNOLOGY · USA

Ascendis Pharma A / S, a biopharmaceutical company, develops therapies for unmet medical needs. The company is headquartered in Hellerup, Denmark.

Regeneron Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Regeneron Pharmaceuticals, Inc. is an American biotechnology company headquartered in Westchester County, New York. Originally focused on neurotrophic factors and their regenerative capabilities, giving rise to its name, the company then branched out into the study of both cytokine and tyrosine kinase receptors.

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