WallStSmart

Arcturus Therapeutics Holdings Inc (ARCT)vsRoyalty Pharma Plc (RPRX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Royalty Pharma Plc generates 4361% more annual revenue ($2.44B vs $54.71M). RPRX leads profitability with a 33.9% profit margin vs -143.8%. RPRX earns a higher WallStSmart Score of 65/100 (C+).

ARCT

Avoid

27

out of 100

Grade: F

Growth: 2.7Profit: 2.0Value: 6.7Quality: 6.5
Piotroski: 2/9Altman Z: -0.17

RPRX

Buy

65

out of 100

Grade: C+

Growth: 6.0Profit: 8.0Value: 4.0Quality: 5.0
Piotroski: 2/9Altman Z: 1.15
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ARCTUndervalued (+78.2%)

Margin of Safety

+78.2%

Fair Value

$33.91

Current Price

$7.30

$26.61 discount

UndervaluedFair: $33.91Overvalued
RPRXSignificantly Overvalued (-59.6%)

Margin of Safety

-59.6%

Fair Value

$34.38

Current Price

$55.02

$20.64 premium

UndervaluedFair: $34.38Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ARCT2 strengths · Avg: 9.5/10
Price/BookValuation
1.1x10/10

Reasonable price relative to book value

Debt/EquityHealth
0.109/10

Conservative balance sheet, low leverage

RPRX3 strengths · Avg: 9.3/10
Profit MarginProfitability
33.9%10/10

Keeps 34 of every $100 in revenue as profit

Operating MarginProfitability
100.3%10/10

Strong operational efficiency at 100.3%

EPS GrowthGrowth
23.2%8/10

Earnings expanding 23.2% YoY

Areas to Watch

ARCT4 concerns · Avg: 3.0/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$220.85M3/10

Smaller company, higher risk/reward

Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

Return on EquityProfitability
-41.1%2/10

ROE of -41.1% — below average capital efficiency

RPRX4 concerns · Avg: 3.5/10
PEG RatioValuation
2.054/10

Expensive relative to growth rate

P/E RatioValuation
28.9x4/10

Moderate valuation

Debt/EquityHealth
1.303/10

Elevated debt levels

Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : ARCT

The strongest argument for ARCT centers on Price/Book, Debt/Equity.

Bull Case : RPRX

The strongest argument for RPRX centers on Profit Margin, Operating Margin, EPS Growth. Profitability is solid with margins at 33.9% and operating margin at 100.3%. Revenue growth of 11.0% demonstrates continued momentum.

Bear Case : ARCT

The primary concerns for ARCT are EPS Growth, Market Cap, Piotroski F-Score.

Bear Case : RPRX

The primary concerns for RPRX are PEG Ratio, P/E Ratio, Debt/Equity.

Key Dynamics to Monitor

ARCT profiles as a turnaround stock while RPRX is a mature play — different risk/reward profiles.

ARCT carries more volatility with a beta of 2.42 — expect wider price swings.

RPRX is growing revenue faster at 11.0% — sustainability is the question.

RPRX generates stronger free cash flow (761M), providing more financial flexibility.

Bottom Line

RPRX scores higher overall (65/100 vs 27/100), backed by strong 33.9% margins and 11.0% revenue growth. ARCT offers better value entry with a 78.2% margin of safety. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Arcturus Therapeutics Holdings Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Arcturus Therapeutics Holdings Inc., an RNA drug company, focuses on the treatment of liver and respiratory diseases. The company is headquartered in San Diego, California.

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Royalty Pharma Plc

HEALTHCARE · BIOTECHNOLOGY · USA

Royalty Pharma plc is a buyer of biopharmaceutical royalties and funder of innovations in the biopharmaceutical industry in the United States. The company is headquartered in New York, New York.

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