WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsPTC Therapeutics Inc (PTCT)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 115% more annual revenue ($3.71B vs $1.73B). PTCT leads profitability with a 39.4% profit margin vs 8.5%. PTCT trades at a lower P/E of 7.5x. ALNY earns a higher WallStSmart Score of 49/100 (D+).

ALNY

Hold

49

out of 100

Grade: D+

Growth: 8.0Profit: 7.0Value: 3.0Quality: 5.0

PTCT

Hold

45

out of 100

Grade: D

Growth: 5.3Profit: 6.0Value: 7.3Quality: 5.3
Piotroski: 5/9Altman Z: 0.22
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYSignificantly Overvalued (-1925.6%)

Margin of Safety

-1925.6%

Fair Value

$15.91

Current Price

$328.70

$312.79 premium

UndervaluedFair: $15.91Overvalued
PTCTSignificantly Overvalued (-21.6%)

Margin of Safety

-21.6%

Fair Value

$58.34

Current Price

$66.75

$8.41 premium

UndervaluedFair: $58.34Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY2 strengths · Avg: 10.0/10
Return on EquityProfitability
73.3%10/10

Every $100 of equity generates 73 in profit

Revenue GrowthGrowth
84.9%10/10

Revenue surging 84.9% year-over-year

PTCT3 strengths · Avg: 9.3/10
P/E RatioValuation
7.5x10/10

Attractively priced relative to earnings

Profit MarginProfitability
39.4%10/10

Keeps 39 of every $100 in revenue as profit

PEG RatioValuation
0.818/10

Growing faster than its price suggests

Areas to Watch

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
131.7x2/10

Premium valuation, high expectations priced in

Price/BookValuation
55.2x2/10

Trading at 55.2x book value

PTCT4 concerns · Avg: 2.5/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Return on EquityProfitability
-77.4%2/10

ROE of -77.4% — below average capital efficiency

Revenue GrowthGrowth
-22.7%2/10

Revenue declined 22.7%

Free Cash FlowQuality
$-36.65M2/10

Negative free cash flow — burning cash

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on Return on Equity, Revenue Growth. Revenue growth of 84.9% demonstrates continued momentum.

Bull Case : PTCT

The strongest argument for PTCT centers on P/E Ratio, Profit Margin, PEG Ratio. Profitability is solid with margins at 39.4% and operating margin at -49.6%. PEG of 0.81 suggests the stock is reasonably priced for its growth.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 131.7x leaves little room for execution misses.

Bear Case : PTCT

The primary concerns for PTCT are EPS Growth, Return on Equity, Revenue Growth.

Key Dynamics to Monitor

ALNY profiles as a hypergrowth stock while PTCT is a declining play — different risk/reward profiles.

PTCT carries more volatility with a beta of 0.56 — expect wider price swings.

ALNY is growing revenue faster at 84.9% — sustainability is the question.

ALNY generates stronger free cash flow (140M), providing more financial flexibility.

Bottom Line

ALNY scores higher overall (49/100 vs 45/100) and 84.9% revenue growth. Both earn "Hold" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

PTC Therapeutics Inc

HEALTHCARE · BIOTECHNOLOGY · USA

PTC Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of drugs for patients with rare disorders. The company is headquartered in South Plainfield, New Jersey.

Want to dig deeper into these stocks?