WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsBlack Diamond Therapeutics Inc (BDTX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 5206% more annual revenue ($3.71B vs $70.00M). BDTX leads profitability with a 32.0% profit margin vs 8.5%. BDTX trades at a lower P/E of 5.7x. BDTX earns a higher WallStSmart Score of 63/100 (C+).

ALNY

Hold

49

out of 100

Grade: D+

Growth: 8.0Profit: 7.0Value: 3.0Quality: 5.0

BDTX

Buy

63

out of 100

Grade: C+

Growth: 4.3Profit: 9.0Value: 7.0Quality: 7.0
Piotroski: 4/9Altman Z: -2.40
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYSignificantly Overvalued (-1925.6%)

Margin of Safety

-1925.6%

Fair Value

$15.91

Current Price

$328.70

$312.79 premium

UndervaluedFair: $15.91Overvalued
BDTXUndervalued (+11.9%)

Margin of Safety

+11.9%

Fair Value

$2.52

Current Price

$2.14

$0.38 discount

UndervaluedFair: $2.52Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY2 strengths · Avg: 10.0/10
Return on EquityProfitability
73.3%10/10

Every $100 of equity generates 73 in profit

Revenue GrowthGrowth
84.9%10/10

Revenue surging 84.9% year-over-year

BDTX6 strengths · Avg: 9.3/10
P/E RatioValuation
5.7x10/10

Attractively priced relative to earnings

Price/BookValuation
1.1x10/10

Reasonable price relative to book value

Profit MarginProfitability
32.0%10/10

Keeps 32 of every $100 in revenue as profit

Return on EquityProfitability
22.9%9/10

Every $100 of equity generates 23 in profit

Debt/EquityHealth
0.139/10

Conservative balance sheet, low leverage

Operating MarginProfitability
28.4%8/10

Strong operational efficiency at 28.4%

Areas to Watch

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
131.7x2/10

Premium valuation, high expectations priced in

Price/BookValuation
55.2x2/10

Trading at 55.2x book value

BDTX4 concerns · Avg: 3.3/10
Revenue GrowthGrowth
0.0%4/10

0.0% revenue growth

EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$120.22M3/10

Smaller company, higher risk/reward

Free Cash FlowQuality
$-6.79M2/10

Negative free cash flow — burning cash

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on Return on Equity, Revenue Growth. Revenue growth of 84.9% demonstrates continued momentum.

Bull Case : BDTX

The strongest argument for BDTX centers on P/E Ratio, Price/Book, Profit Margin. Profitability is solid with margins at 32.0% and operating margin at 28.4%.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 131.7x leaves little room for execution misses.

Bear Case : BDTX

The primary concerns for BDTX are Revenue Growth, EPS Growth, Market Cap.

Key Dynamics to Monitor

ALNY profiles as a hypergrowth stock while BDTX is a value play — different risk/reward profiles.

BDTX carries more volatility with a beta of 3.43 — expect wider price swings.

ALNY is growing revenue faster at 84.9% — sustainability is the question.

ALNY generates stronger free cash flow (140M), providing more financial flexibility.

Bottom Line

BDTX scores higher overall (63/100 vs 49/100), backed by strong 32.0% margins. Both earn "Buy" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

Black Diamond Therapeutics Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Black Diamond Therapeutics, Inc., a biotechnology company, discovers and develops small molecule tumor agnostic therapies. The company is headquartered in Cambridge, Massachusetts.

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