WallStSmart

Alector Inc (ALEC)vsAstraZeneca PLC (AZN)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 328070% more annual revenue ($60.44B vs $18.42M). AZN leads profitability with a 17.2% profit margin vs 0.0%. AZN earns a higher WallStSmart Score of 64/100 (C+).

ALEC

Avoid

17

out of 100

Grade: F

Growth: 2.0Profit: 2.5Value: 6.7Quality: 5.0
Piotroski: 4/9Altman Z: -5.30

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.0Profit: 8.5Value: 6.0Quality: 5.0
Piotroski: 6/9Altman Z: 1.48
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALECUndervalued (+47.3%)

Margin of Safety

+47.3%

Fair Value

$3.64

Current Price

$1.52

$2.12 discount

UndervaluedFair: $3.64Overvalued
AZNUndervalued (+10.7%)

Margin of Safety

+10.7%

Fair Value

$193.96

Current Price

$172.48

$21.48 discount

UndervaluedFair: $193.96Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALEC0 strengths · Avg: 0/10

No standout strengths identified

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$261.94B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
20.7%9/10

Every $100 of equity generates 21 in profit

Operating MarginProfitability
27.9%8/10

Strong operational efficiency at 27.9%

Free Cash FlowQuality
$2.13B8/10

Generating 2.1B in free cash flow

Areas to Watch

ALEC4 concerns · Avg: 3.0/10
Price/BookValuation
16.9x4/10

Trading at 16.9x book value

Market CapQuality
$169.87M3/10

Smaller company, higher risk/reward

Profit MarginProfitability
0.0%3/10

0.0% margin — thin

Return on EquityProfitability
-238.9%2/10

ROE of -238.9% — below average capital efficiency

AZN2 concerns · Avg: 3.0/10
P/E RatioValuation
25.4x4/10

Moderate valuation

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

Comparative Analysis Report

WallStSmart Research

Bull Case : ALEC

ALEC has a balanced fundamental profile.

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.2% and operating margin at 27.9%. Revenue growth of 12.5% demonstrates continued momentum.

Bear Case : ALEC

The primary concerns for ALEC are Price/Book, Market Cap, Profit Margin. Debt-to-equity of 3.33 is elevated, increasing financial risk.

Bear Case : AZN

The primary concerns for AZN are P/E Ratio, Altman Z-Score.

Key Dynamics to Monitor

ALEC profiles as a value stock while AZN is a mature play — different risk/reward profiles.

ALEC carries more volatility with a beta of 0.60 — expect wider price swings.

AZN is growing revenue faster at 12.5% — sustainability is the question.

AZN generates stronger free cash flow (2.1B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (64/100 vs 17/100), backed by strong 17.2% margins and 12.5% revenue growth. ALEC offers better value entry with a 47.3% margin of safety. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alector Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alector, Inc., a clinical-stage biopharmaceutical company, develops therapies for the treatment of neurodegenerative diseases. The company is headquartered in South San Francisco, California.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

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