WallStSmart

Adaptive Biotechnologies Corp (ADPT)vsAlnylam Pharmaceuticals Inc (ALNY)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 1241% more annual revenue ($3.71B vs $276.98M). ALNY leads profitability with a 8.5% profit margin vs -21.5%. ALNY earns a higher WallStSmart Score of 49/100 (D+).

ADPT

Avoid

32

out of 100

Grade: F

Growth: 7.3Profit: 2.0Value: 5.0Quality: 7.0
Piotroski: 5/9Altman Z: -2.53

ALNY

Hold

49

out of 100

Grade: D+

Growth: 8.0Profit: 7.0Value: 3.0Quality: 5.0
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

Intrinsic value data unavailable for ADPT.

ALNYSignificantly Overvalued (-1925.6%)

Margin of Safety

-1925.6%

Fair Value

$15.91

Current Price

$328.70

$312.79 premium

UndervaluedFair: $15.91Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ADPT1 strengths · Avg: 10.0/10
Revenue GrowthGrowth
51.0%10/10

Revenue surging 51.0% year-over-year

ALNY2 strengths · Avg: 10.0/10
Return on EquityProfitability
73.3%10/10

Every $100 of equity generates 73 in profit

Revenue GrowthGrowth
84.9%10/10

Revenue surging 84.9% year-over-year

Areas to Watch

ADPT4 concerns · Avg: 3.3/10
Price/BookValuation
10.0x4/10

Trading at 10.0x book value

EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Debt/EquityHealth
1.283/10

Elevated debt levels

Return on EquityProfitability
-27.8%2/10

ROE of -27.8% — below average capital efficiency

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
131.7x2/10

Premium valuation, high expectations priced in

Price/BookValuation
55.2x2/10

Trading at 55.2x book value

Comparative Analysis Report

WallStSmart Research

Bull Case : ADPT

The strongest argument for ADPT centers on Revenue Growth. Revenue growth of 51.0% demonstrates continued momentum.

Bull Case : ALNY

The strongest argument for ALNY centers on Return on Equity, Revenue Growth. Revenue growth of 84.9% demonstrates continued momentum.

Bear Case : ADPT

The primary concerns for ADPT are Price/Book, EPS Growth, Debt/Equity.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 131.7x leaves little room for execution misses.

Key Dynamics to Monitor

ADPT carries more volatility with a beta of 2.30 — expect wider price swings.

ALNY is growing revenue faster at 84.9% — sustainability is the question.

ALNY generates stronger free cash flow (140M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

ALNY scores higher overall (49/100 vs 32/100) and 84.9% revenue growth. Both earn "Hold" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Adaptive Biotechnologies Corp

HEALTHCARE · BIOTECHNOLOGY · USA

Adaptive Biotechnologies Corporation, a commercial-stage company, develops an immune medicine platform for the diagnosis and treatment of various diseases. The company is headquartered in Seattle, Washington.

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Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

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