WallStSmart

Arbutus Biopharma Corp (ABUS)vsAlnylam Pharmaceuticals Inc (ALNY)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 2139% more annual revenue ($4.29B vs $191.44M). ABUS leads profitability with a 84.0% profit margin vs 12.6%. ABUS trades at a lower P/E of 5.4x. ALNY earns a higher WallStSmart Score of 65/100 (B-).

ABUS

Buy

63

out of 100

Grade: C+

Growth: 5.3Profit: 10.0Value: 6.7Quality: 7.0
Piotroski: 4/9Altman Z: -17.55

ALNY

Strong Buy

65

out of 100

Grade: B-

Growth: 8.0Profit: 8.0Value: 7.3Quality: 5.5
Piotroski: 4/9Altman Z: -0.07
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

Intrinsic value data unavailable for ABUS.

ALNYUndervalued (+86.4%)

Margin of Safety

+86.4%

Fair Value

$2372.19

Current Price

$303.05

$2069.14 discount

UndervaluedFair: $2372.19Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ABUS6 strengths · Avg: 10.0/10
P/E RatioValuation
5.4x10/10

Attractively priced relative to earnings

Return on EquityProfitability
61.8%10/10

Every $100 of equity generates 62 in profit

Profit MarginProfitability
84.0%10/10

Keeps 84 of every $100 in revenue as profit

Operating MarginProfitability
94.4%10/10

Strong operational efficiency at 94.4%

Revenue GrowthGrowth
10055.0%10/10

Revenue surging 10055.0% year-over-year

Debt/EquityHealth
0.0010/10

Conservative balance sheet, low leverage

ALNY4 strengths · Avg: 9.5/10
PEG RatioValuation
0.4810/10

Growing faster than its price suggests

Return on EquityProfitability
53.7%10/10

Every $100 of equity generates 54 in profit

Revenue GrowthGrowth
96.4%10/10

Revenue surging 96.4% year-over-year

Operating MarginProfitability
23.0%8/10

Strong operational efficiency at 23.0%

Areas to Watch

ABUS4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$884.97M3/10

Smaller company, higher risk/reward

Free Cash FlowQuality
$-8.11M2/10

Negative free cash flow — burning cash

Altman Z-ScoreHealth
-17.552/10

Distress zone — elevated risk

ALNY4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Debt/EquityHealth
1.183/10

Elevated debt levels

P/E RatioValuation
70.9x2/10

Premium valuation, high expectations priced in

Price/BookValuation
37.6x2/10

Trading at 37.6x book value

Comparative Analysis Report

WallStSmart Research

Bull Case : ABUS

The strongest argument for ABUS centers on P/E Ratio, Return on Equity, Profit Margin. Profitability is solid with margins at 84.0% and operating margin at 94.4%. Revenue growth of 10055.0% demonstrates continued momentum.

Bull Case : ALNY

The strongest argument for ALNY centers on PEG Ratio, Return on Equity, Revenue Growth. Revenue growth of 96.4% demonstrates continued momentum. PEG of 0.48 suggests the stock is reasonably priced for its growth.

Bear Case : ABUS

The primary concerns for ABUS are EPS Growth, Market Cap, Free Cash Flow.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, Debt/Equity, P/E Ratio. A P/E of 70.9x leaves little room for execution misses.

Key Dynamics to Monitor

ABUS carries more volatility with a beta of 0.62 — expect wider price swings.

ABUS is growing revenue faster at 10055.0% — sustainability is the question.

ALNY generates stronger free cash flow (49M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

ALNY scores higher overall (65/100 vs 63/100) and 96.4% revenue growth. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Arbutus Biopharma Corp

HEALTHCARE · BIOTECHNOLOGY · USA

Arbutus Biopharma Corporation, a biopharmaceutical company, is dedicated to the discovery, development, and commercialization of a cure for patients with chronic hepatitis B virus (HBV) infection in the United States. The company is headquartered in Warminster, Pennsylvania.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

Want to dig deeper into these stocks?