WallStSmart

Abeona Therapeutics Inc (ABEO)vsAstraZeneca PLC (AZN)

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Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 415574% more annual revenue ($60.44B vs $14.54M). ABEO leads profitability with a 454.9% profit margin vs 17.2%. ABEO trades at a lower P/E of 5.9x. AZN earns a higher WallStSmart Score of 64/100 (C+).

ABEO

Hold

43

out of 100

Grade: D

Growth: 5.3Profit: 6.0Value: 6.7Quality: 7.5
Piotroski: 6/9Altman Z: -3.51

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.0Profit: 8.5Value: 6.0Quality: 5.0
Piotroski: 6/9Altman Z: 1.48
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

Intrinsic value data unavailable for ABEO.

AZNUndervalued (+8.2%)

Margin of Safety

+8.2%

Fair Value

$194.77

Current Price

$185.95

$8.82 discount

UndervaluedFair: $194.77Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ABEO5 strengths · Avg: 9.4/10
P/E RatioValuation
5.9x10/10

Attractively priced relative to earnings

Return on EquityProfitability
45.6%10/10

Every $100 of equity generates 46 in profit

Profit MarginProfitability
454.9%10/10

Keeps 455 of every $100 in revenue as profit

Debt/EquityHealth
0.169/10

Conservative balance sheet, low leverage

Price/BookValuation
2.1x8/10

Reasonable price relative to book value

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$282.69B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
21.9%9/10

Every $100 of equity generates 22 in profit

Operating MarginProfitability
27.9%8/10

Strong operational efficiency at 27.9%

Free Cash FlowQuality
$1.82B8/10

Generating 1.8B in free cash flow

Areas to Watch

ABEO4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$320.88M3/10

Smaller company, higher risk/reward

Revenue GrowthGrowth
-100.0%2/10

Revenue declined 100.0%

Free Cash FlowQuality
$-20.74M2/10

Negative free cash flow — burning cash

AZN2 concerns · Avg: 3.0/10
P/E RatioValuation
27.5x4/10

Moderate valuation

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

Comparative Analysis Report

WallStSmart Research

Bull Case : ABEO

The strongest argument for ABEO centers on P/E Ratio, Return on Equity, Profit Margin. Profitability is solid with margins at 454.9% and operating margin at -264.1%.

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.2% and operating margin at 27.9%. Revenue growth of 12.5% demonstrates continued momentum.

Bear Case : ABEO

The primary concerns for ABEO are EPS Growth, Market Cap, Revenue Growth.

Bear Case : AZN

The primary concerns for AZN are P/E Ratio, Altman Z-Score.

Key Dynamics to Monitor

ABEO profiles as a declining stock while AZN is a mature play — different risk/reward profiles.

ABEO carries more volatility with a beta of 1.34 — expect wider price swings.

AZN is growing revenue faster at 12.5% — sustainability is the question.

AZN generates stronger free cash flow (1.8B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (64/100 vs 43/100), backed by strong 17.2% margins and 12.5% revenue growth. Both earn "Buy" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Abeona Therapeutics Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Abeona Therapeutics Inc., a clinical-stage biopharmaceutical company, develops gene and cell therapies for rare, life-threatening genetic diseases. The company is headquartered in New York, New York.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

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