WallStSmart

Insmed Inc (INSM)vsIonis Pharmaceuticals Inc (IONS)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Ionis Pharmaceuticals Inc generates 56% more annual revenue ($943.71M vs $606.42M). INSM leads profitability with a -2.1% profit margin vs -40.4%. INSM appears more attractively valued with a PEG of 1.09. INSM earns a higher WallStSmart Score of 39/100 (F).

INSM

Hold

39

out of 100

Grade: F

Growth: 6.0Profit: 2.0Value: 6.7Quality: 6.3
Piotroski: 6/9Altman Z: -3.77

IONS

Avoid

21

out of 100

Grade: F

Growth: 4.0Profit: 2.0Value: 4.0Quality: 5.3
Piotroski: 4/9Altman Z: 0.00

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

INSM0 strengths · Avg: 0/10

No standout strengths identified

IONS0 strengths · Avg: 0/10

No standout strengths identified

Areas to Watch

INSM4 concerns · Avg: 3.0/10
Revenue GrowthGrowth
1.5%4/10

1.5% revenue growth

EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Price/BookValuation
43.0x2/10

Trading at 43.0x book value

Return on EquityProfitability
-2.5%2/10

ROE of -2.5% — below average capital efficiency

IONS4 concerns · Avg: 2.0/10
PEG RatioValuation
25.702/10

Expensive relative to growth rate

Price/BookValuation
24.2x2/10

Trading at 24.2x book value

Return on EquityProfitability
-70.8%2/10

ROE of -70.8% — below average capital efficiency

Revenue GrowthGrowth
-10.3%2/10

Revenue declined 10.3%

Comparative Analysis Report

WallStSmart Research

Bull Case : INSM

PEG of 1.09 suggests the stock is reasonably priced for its growth.

Bull Case : IONS

IONS has a balanced fundamental profile.

Bear Case : INSM

The primary concerns for INSM are Revenue Growth, EPS Growth, Price/Book.

Bear Case : IONS

The primary concerns for IONS are PEG Ratio, Price/Book, Return on Equity.

Key Dynamics to Monitor

INSM carries more volatility with a beta of 1.17 — expect wider price swings.

INSM is growing revenue faster at 1.5% — sustainability is the question.

IONS generates stronger free cash flow (-159M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

INSM scores higher overall (39/100 vs 21/100). Both earn "Hold" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Insmed Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Insmed Incorporated, a biopharmaceutical company, develops and markets therapies for patients with rare and serious diseases. The company is headquartered in Bridgewater, New Jersey.

Ionis Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapies in the United States. The company is headquartered in Carlsbad, California.

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