WallStSmart

Ginkgo Bioworks Holdings (DNA)vsRoyalty Pharma Plc (RPRX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Royalty Pharma Plc generates 1512% more annual revenue ($2.44B vs $151.40M). RPRX leads profitability with a 33.9% profit margin vs -201.0%. RPRX earns a higher WallStSmart Score of 65/100 (C+).

DNA

Avoid

29

out of 100

Grade: F

Growth: 2.7Profit: 2.0Value: 4.7Quality: 5.5
Piotroski: 2/9Altman Z: -7.56

RPRX

Buy

65

out of 100

Grade: C+

Growth: 6.0Profit: 8.0Value: 3.3Quality: 5.0
Piotroski: 2/9Altman Z: 1.15
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

DNAOvervalued (-8.0%)

Margin of Safety

-8.0%

Fair Value

$8.66

Current Price

$9.37

$0.71 premium

UndervaluedFair: $8.66Overvalued
RPRXSignificantly Overvalued (-66.8%)

Margin of Safety

-66.8%

Fair Value

$35.03

Current Price

$57.75

$22.72 premium

UndervaluedFair: $35.03Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

DNA1 strengths · Avg: 10.0/10
Price/BookValuation
1.3x10/10

Reasonable price relative to book value

RPRX3 strengths · Avg: 9.3/10
Profit MarginProfitability
33.9%10/10

Keeps 34 of every $100 in revenue as profit

Operating MarginProfitability
100.3%10/10

Strong operational efficiency at 100.3%

EPS GrowthGrowth
23.2%8/10

Earnings expanding 23.2% YoY

Areas to Watch

DNA4 concerns · Avg: 3.0/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$518.02M3/10

Smaller company, higher risk/reward

Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

Return on EquityProfitability
-68.7%2/10

ROE of -68.7% — below average capital efficiency

RPRX4 concerns · Avg: 3.5/10
PEG RatioValuation
2.194/10

Expensive relative to growth rate

P/E RatioValuation
30.8x4/10

Premium valuation, high expectations priced in

Debt/EquityHealth
1.303/10

Elevated debt levels

Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : DNA

The strongest argument for DNA centers on Price/Book.

Bull Case : RPRX

The strongest argument for RPRX centers on Profit Margin, Operating Margin, EPS Growth. Profitability is solid with margins at 33.9% and operating margin at 100.3%. Revenue growth of 11.0% demonstrates continued momentum.

Bear Case : DNA

The primary concerns for DNA are EPS Growth, Market Cap, Piotroski F-Score.

Bear Case : RPRX

The primary concerns for RPRX are PEG Ratio, P/E Ratio, Debt/Equity.

Key Dynamics to Monitor

DNA profiles as a turnaround stock while RPRX is a mature play — different risk/reward profiles.

DNA carries more volatility with a beta of 1.78 — expect wider price swings.

RPRX is growing revenue faster at 11.0% — sustainability is the question.

RPRX generates stronger free cash flow (761M), providing more financial flexibility.

Bottom Line

RPRX scores higher overall (65/100 vs 29/100), backed by strong 33.9% margins and 11.0% revenue growth. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Ginkgo Bioworks Holdings

HEALTHCARE · BIOTECHNOLOGY · USA

Ginkgo Bioworks Holdings (DNA) is a pioneering force in synthetic biology, leveraging advanced genetic engineering to create customized bioengineered organisms suitable for a wide range of sectors, including pharmaceuticals, agriculture, and industrial biotechnology. The company's innovative platform streamlines cellular design and manufacturing, positioning Ginkgo as a key player in addressing critical global challenges such as climate change and food security. With a strong focus on sustainable biotechnology solutions, Ginkgo is well-equipped to tap into the increasing market demand for bio-based alternatives, highlighting its potential for significant growth and transformative impact across various industries.

Royalty Pharma Plc

HEALTHCARE · BIOTECHNOLOGY · USA

Royalty Pharma plc is a buyer of biopharmaceutical royalties and funder of innovations in the biopharmaceutical industry in the United States. The company is headquartered in New York, New York.

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