WallStSmart

AstraZeneca PLC (AZN)vsRigel Pharmaceuticals Inc (RIGL)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 20062% more annual revenue ($60.44B vs $299.77M). RIGL leads profitability with a 121.5% profit margin vs 17.2%. RIGL trades at a lower P/E of 1.7x. RIGL earns a higher WallStSmart Score of 65/100 (B-).

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.0Profit: 8.5Value: 6.0Quality: 5.0
Piotroski: 6/9Altman Z: 1.48

RIGL

Strong Buy

65

out of 100

Grade: B-

Growth: 6.0Profit: 9.5Value: 8.3Quality: 6.5
Piotroski: 5/9Altman Z: 0.87
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AZNUndervalued (+8.2%)

Margin of Safety

+8.2%

Fair Value

$194.77

Current Price

$185.95

$8.82 discount

UndervaluedFair: $194.77Overvalued
RIGLUndervalued (+87.7%)

Margin of Safety

+87.7%

Fair Value

$283.28

Current Price

$29.93

$253.35 discount

UndervaluedFair: $283.28Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$282.69B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
21.9%9/10

Every $100 of equity generates 22 in profit

Operating MarginProfitability
27.9%8/10

Strong operational efficiency at 27.9%

Free Cash FlowQuality
$1.82B8/10

Generating 1.8B in free cash flow

RIGL6 strengths · Avg: 9.5/10
P/E RatioValuation
1.7x10/10

Attractively priced relative to earnings

Price/BookValuation
1.4x10/10

Reasonable price relative to book value

Return on EquityProfitability
91.1%10/10

Every $100 of equity generates 91 in profit

Profit MarginProfitability
121.5%10/10

Keeps 122 of every $100 in revenue as profit

Debt/EquityHealth
0.119/10

Conservative balance sheet, low leverage

Operating MarginProfitability
20.2%8/10

Strong operational efficiency at 20.2%

Areas to Watch

AZN2 concerns · Avg: 3.0/10
P/E RatioValuation
27.5x4/10

Moderate valuation

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

RIGL3 concerns · Avg: 2.3/10
Market CapQuality
$593.55M3/10

Smaller company, higher risk/reward

EPS GrowthGrowth
-30.2%2/10

Earnings declined 30.2%

Altman Z-ScoreHealth
0.872/10

Distress zone — elevated risk

Comparative Analysis Report

WallStSmart Research

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.2% and operating margin at 27.9%. Revenue growth of 12.5% demonstrates continued momentum.

Bull Case : RIGL

The strongest argument for RIGL centers on P/E Ratio, Price/Book, Return on Equity. Profitability is solid with margins at 121.5% and operating margin at 20.2%. Revenue growth of 10.3% demonstrates continued momentum.

Bear Case : AZN

The primary concerns for AZN are P/E Ratio, Altman Z-Score.

Bear Case : RIGL

The primary concerns for RIGL are Market Cap, EPS Growth, Altman Z-Score.

Key Dynamics to Monitor

RIGL carries more volatility with a beta of 1.18 — expect wider price swings.

AZN is growing revenue faster at 12.5% — sustainability is the question.

AZN generates stronger free cash flow (1.8B), providing more financial flexibility.

Monitor DRUG MANUFACTURERS - GENERAL industry trends, competitive dynamics, and regulatory changes.

Bottom Line

RIGL scores higher overall (65/100 vs 64/100), backed by strong 121.5% margins and 10.3% revenue growth. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

Rigel Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Rigel Pharmaceuticals, Inc., a biotechnology company, discovers and develops small molecule drugs to treat blood disorders, cancer, and rare immune diseases. The company is headquartered in South San Francisco, California.

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