WallStSmart

AstraZeneca PLC (AZN)vsQ32 Bio Inc (QTTB)

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Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 112372% more annual revenue ($60.44B vs $53.74M). QTTB leads profitability with a 61.9% profit margin vs 17.2%. QTTB trades at a lower P/E of 4.3x. AZN earns a higher WallStSmart Score of 64/100 (C+).

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.0Profit: 8.5Value: 6.0Quality: 5.0
Piotroski: 6/9Altman Z: 1.48

QTTB

Buy

54

out of 100

Grade: C-

Growth: 6.0Profit: 10.0Value: 6.7Quality: 7.0
Piotroski: 5/9Altman Z: -0.75
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AZNUndervalued (+10.1%)

Margin of Safety

+10.1%

Fair Value

$194.57

Current Price

$185.95

$8.62 discount

UndervaluedFair: $194.57Overvalued

Intrinsic value data unavailable for QTTB.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$282.69B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
21.9%9/10

Every $100 of equity generates 22 in profit

Operating MarginProfitability
27.9%8/10

Strong operational efficiency at 27.9%

Free Cash FlowQuality
$1.82B8/10

Generating 1.8B in free cash flow

QTTB5 strengths · Avg: 9.8/10
P/E RatioValuation
4.3x10/10

Attractively priced relative to earnings

Return on EquityProfitability
71.8%10/10

Every $100 of equity generates 72 in profit

Profit MarginProfitability
61.9%10/10

Keeps 62 of every $100 in revenue as profit

Operating MarginProfitability
39.8%10/10

Strong operational efficiency at 39.8%

Debt/EquityHealth
0.299/10

Conservative balance sheet, low leverage

Areas to Watch

AZN2 concerns · Avg: 3.0/10
P/E RatioValuation
27.5x4/10

Moderate valuation

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

QTTB4 concerns · Avg: 3.3/10
Revenue GrowthGrowth
0.0%4/10

0.0% revenue growth

EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$218.23M3/10

Smaller company, higher risk/reward

Free Cash FlowQuality
$-6.34M2/10

Negative free cash flow — burning cash

Comparative Analysis Report

WallStSmart Research

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.2% and operating margin at 27.9%. Revenue growth of 12.5% demonstrates continued momentum.

Bull Case : QTTB

The strongest argument for QTTB centers on P/E Ratio, Return on Equity, Profit Margin. Profitability is solid with margins at 61.9% and operating margin at 39.8%.

Bear Case : AZN

The primary concerns for AZN are P/E Ratio, Altman Z-Score.

Bear Case : QTTB

The primary concerns for QTTB are Revenue Growth, EPS Growth, Market Cap.

Key Dynamics to Monitor

AZN profiles as a mature stock while QTTB is a value play — different risk/reward profiles.

AZN carries more volatility with a beta of 0.21 — expect wider price swings.

AZN is growing revenue faster at 12.5% — sustainability is the question.

AZN generates stronger free cash flow (1.8B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (64/100 vs 54/100), backed by strong 17.2% margins and 12.5% revenue growth. Both earn "Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

Q32 Bio Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Q32 Bio Inc. (QTTB) is an innovative biotechnology company specializing in the development of cutting-edge antibody-based therapies aimed at treating autoimmune diseases and optimizing immune responses. With its proprietary technology platform, Q32 Bio is advancing a diverse pipeline of therapeutic candidates poised to restore immune balance and address critical unmet medical needs. Supported by a highly experienced management team and strategic partnerships, Q32 Bio is strategically positioned to drive meaningful advancements in healthcare, ultimately creating long-term value for shareholders through its commitment to ongoing research and development excellence.

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