WallStSmart

AstraZeneca PLC (AZN)vsPuma Biotechnology Inc (PBYI)

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Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 25621% more annual revenue ($58.74B vs $228.37M). AZN leads profitability with a 17.4% profit margin vs 13.6%. PBYI appears more attractively valued with a PEG of 0.03. PBYI earns a higher WallStSmart Score of 71/100 (B).

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.7Profit: 8.0Value: 5.3Quality: 5.0
Piotroski: 6/9Altman Z: 1.48

PBYI

Strong Buy

71

out of 100

Grade: B

Growth: 4.7Profit: 8.0Value: 9.3Quality: 5.0
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AZNUndervalued (+4.1%)

Margin of Safety

+4.1%

Fair Value

$214.51

Current Price

$187.37

$27.14 discount

UndervaluedFair: $214.51Overvalued
PBYIUndervalued (+76.6%)

Margin of Safety

+76.6%

Fair Value

$28.43

Current Price

$7.48

$20.95 discount

UndervaluedFair: $28.43Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AZN5 strengths · Avg: 9.0/10
Market CapQuality
$287.11B10/10

Mega-cap, among the largest globally

EPS GrowthGrowth
53.9%10/10

Earnings expanding 53.9% YoY

Return on EquityProfitability
22.8%9/10

Every $100 of equity generates 23 in profit

Operating MarginProfitability
21.6%8/10

Strong operational efficiency at 21.6%

Free Cash FlowQuality
$1.38B8/10

Generating 1.4B in free cash flow

PBYI6 strengths · Avg: 8.5/10
PEG RatioValuation
0.0310/10

Growing faster than its price suggests

Return on EquityProfitability
28.0%9/10

Every $100 of equity generates 28 in profit

P/E RatioValuation
12.3x8/10

Attractively priced relative to earnings

Price/BookValuation
2.9x8/10

Reasonable price relative to book value

Operating MarginProfitability
22.7%8/10

Strong operational efficiency at 22.7%

Revenue GrowthGrowth
27.7%8/10

Revenue surging 27.7% year-over-year

Areas to Watch

AZN4 concerns · Avg: 3.5/10
PEG RatioValuation
1.544/10

Expensive relative to growth rate

P/E RatioValuation
27.9x4/10

Moderate valuation

Revenue GrowthGrowth
4.1%4/10

4.1% revenue growth

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

PBYI2 concerns · Avg: 2.5/10
Market CapQuality
$382.08M3/10

Smaller company, higher risk/reward

EPS GrowthGrowth
-34.4%2/10

Earnings declined 34.4%

Comparative Analysis Report

WallStSmart Research

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, EPS Growth, Return on Equity. Profitability is solid with margins at 17.4% and operating margin at 21.6%.

Bull Case : PBYI

The strongest argument for PBYI centers on PEG Ratio, Return on Equity, P/E Ratio. Revenue growth of 27.7% demonstrates continued momentum. PEG of 0.03 suggests the stock is reasonably priced for its growth.

Bear Case : AZN

The primary concerns for AZN are PEG Ratio, P/E Ratio, Revenue Growth.

Bear Case : PBYI

The primary concerns for PBYI are Market Cap, EPS Growth.

Key Dynamics to Monitor

AZN profiles as a value stock while PBYI is a growth play — different risk/reward profiles.

PBYI carries more volatility with a beta of 1.18 — expect wider price swings.

PBYI is growing revenue faster at 27.7% — sustainability is the question.

AZN generates stronger free cash flow (1.4B), providing more financial flexibility.

Bottom Line

PBYI scores higher overall (71/100 vs 64/100) and 27.7% revenue growth. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

Puma Biotechnology Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to improve cancer care in the United States and internationally. The company is headquartered in Los Angeles, California.

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