WallStSmart

AstraZeneca PLC (AZN)vsPuma Biotechnology Inc (PBYI)

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Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 26437% more annual revenue ($61.37B vs $231.24M). AZN leads profitability with a 17.0% profit margin vs 11.6%. PBYI appears more attractively valued with a PEG of 0.03. PBYI earns a higher WallStSmart Score of 67/100 (B-).

AZN

Buy

60

out of 100

Grade: C+

Growth: 5.3Profit: 8.0Value: 6.7Quality: 5.0
Piotroski: 6/9Altman Z: 1.48

PBYI

Strong Buy

67

out of 100

Grade: B-

Growth: 6.7Profit: 7.0Value: 8.7Quality: 6.5
Piotroski: 4/9Altman Z: -5.24
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AZNUndervalued (+18.4%)

Margin of Safety

+18.4%

Fair Value

$196.10

Current Price

$160.17

$35.93 discount

UndervaluedFair: $196.10Overvalued
PBYIUndervalued (+68.6%)

Margin of Safety

+68.6%

Fair Value

$21.16

Current Price

$9.12

$12.04 discount

UndervaluedFair: $21.16Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$252.33B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
20.8%9/10

Every $100 of equity generates 21 in profit

Operating MarginProfitability
23.5%8/10

Strong operational efficiency at 23.5%

Free Cash FlowQuality
$2.13B8/10

Generating 2.1B in free cash flow

PBYI3 strengths · Avg: 9.3/10
PEG RatioValuation
0.0310/10

Growing faster than its price suggests

Debt/EquityHealth
0.0310/10

Conservative balance sheet, low leverage

EPS GrowthGrowth
35.8%8/10

Earnings expanding 35.8% YoY

Areas to Watch

AZN2 concerns · Avg: 3.0/10
EPS GrowthGrowth
2.5%4/10

2.5% earnings growth

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

PBYI2 concerns · Avg: 2.5/10
Market CapQuality
$492.97M3/10

Smaller company, higher risk/reward

Altman Z-ScoreHealth
-5.242/10

Distress zone — elevated risk

Comparative Analysis Report

WallStSmart Research

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.0% and operating margin at 23.5%. PEG of 1.28 suggests the stock is reasonably priced for its growth.

Bull Case : PBYI

The strongest argument for PBYI centers on PEG Ratio, Debt/Equity, EPS Growth. PEG of 0.03 suggests the stock is reasonably priced for its growth.

Bear Case : AZN

The primary concerns for AZN are EPS Growth, Altman Z-Score.

Bear Case : PBYI

The primary concerns for PBYI are Market Cap, Altman Z-Score.

Key Dynamics to Monitor

AZN profiles as a mature stock while PBYI is a value play — different risk/reward profiles.

PBYI carries more volatility with a beta of 1.23 — expect wider price swings.

PBYI is growing revenue faster at 7.8% — sustainability is the question.

AZN generates stronger free cash flow (2.1B), providing more financial flexibility.

Bottom Line

PBYI scores higher overall (67/100 vs 60/100). AZN offers better value entry with a 18.4% margin of safety. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

Puma Biotechnology Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to improve cancer care in the United States and internationally. The company is headquartered in Los Angeles, California.

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