WallStSmart

AstraZeneca PLC (AZN)vsMeiraGTx Holdings PLC (MGTX)

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Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 15338% more annual revenue ($61.37B vs $397.50M). MGTX leads profitability with a 19.9% profit margin vs 17.0%. MGTX trades at a lower P/E of 10.7x. AZN earns a higher WallStSmart Score of 62/100 (C+).

AZN

Buy

62

out of 100

Grade: C+

Growth: 5.3Profit: 8.0Value: 6.0Quality: 5.0
Piotroski: 6/9Altman Z: 1.48

MGTX

Buy

61

out of 100

Grade: C+

Growth: 8.0Profit: 9.5Value: 6.7Quality: 6.0
Piotroski: 5/9Altman Z: -5.87
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AZNUndervalued (+13.1%)

Margin of Safety

+13.1%

Fair Value

$194.96

Current Price

$169.51

$25.45 discount

UndervaluedFair: $194.96Overvalued

Intrinsic value data unavailable for MGTX.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$263.78B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
20.8%9/10

Every $100 of equity generates 21 in profit

Operating MarginProfitability
23.5%8/10

Strong operational efficiency at 23.5%

Free Cash FlowQuality
$2.13B8/10

Generating 2.1B in free cash flow

MGTX4 strengths · Avg: 10.0/10
P/E RatioValuation
10.7x10/10

Attractively priced relative to earnings

Return on EquityProfitability
36.6%10/10

Every $100 of equity generates 37 in profit

Operating MarginProfitability
76.0%10/10

Strong operational efficiency at 76.0%

Revenue GrowthGrowth
8609.0%10/10

Revenue surging 8609.0% year-over-year

Areas to Watch

AZN3 concerns · Avg: 3.3/10
P/E RatioValuation
25.4x4/10

Moderate valuation

EPS GrowthGrowth
2.5%4/10

2.5% earnings growth

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

MGTX4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$884.56M3/10

Smaller company, higher risk/reward

Free Cash FlowQuality
$-40.55M2/10

Negative free cash flow — burning cash

Altman Z-ScoreHealth
-5.872/10

Distress zone — elevated risk

Comparative Analysis Report

WallStSmart Research

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.0% and operating margin at 23.5%. PEG of 1.22 suggests the stock is reasonably priced for its growth.

Bull Case : MGTX

The strongest argument for MGTX centers on P/E Ratio, Return on Equity, Operating Margin. Profitability is solid with margins at 19.9% and operating margin at 76.0%. Revenue growth of 8609.0% demonstrates continued momentum.

Bear Case : AZN

The primary concerns for AZN are P/E Ratio, EPS Growth, Altman Z-Score.

Bear Case : MGTX

The primary concerns for MGTX are EPS Growth, Market Cap, Free Cash Flow.

Key Dynamics to Monitor

AZN profiles as a mature stock while MGTX is a growth play — different risk/reward profiles.

MGTX carries more volatility with a beta of 1.35 — expect wider price swings.

MGTX is growing revenue faster at 8609.0% — sustainability is the question.

AZN generates stronger free cash flow (2.1B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (62/100 vs 61/100), backed by strong 17.0% margins. Both earn "Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

MeiraGTx Holdings PLC

HEALTHCARE · BIOTECHNOLOGY · USA

MeiraGTx Holdings plc, a clinical-stage gene therapy company, focused on developing treatments for patients living with serious illnesses. The company is headquartered in New York, New York.

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