WallStSmart

AstraZeneca PLC (AZN)vsIronwood Pharmaceuticals Inc (IRWD)

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Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 16618% more annual revenue ($60.44B vs $361.51M). IRWD leads profitability with a 28.3% profit margin vs 17.2%. IRWD trades at a lower P/E of 5.3x. IRWD earns a higher WallStSmart Score of 69/100 (B-).

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.0Profit: 8.5Value: 6.0Quality: 5.0
Piotroski: 6/9Altman Z: 1.48

IRWD

Strong Buy

69

out of 100

Grade: B-

Growth: 7.3Profit: 8.0Value: 8.3Quality: 5.5
Piotroski: 4/9Altman Z: -4.21
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AZNUndervalued (+8.2%)

Margin of Safety

+8.2%

Fair Value

$194.77

Current Price

$185.95

$8.82 discount

UndervaluedFair: $194.77Overvalued
IRWDUndervalued (+86.3%)

Margin of Safety

+86.3%

Fair Value

$32.43

Current Price

$3.31

$29.12 discount

UndervaluedFair: $32.43Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$282.69B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
21.9%9/10

Every $100 of equity generates 22 in profit

Operating MarginProfitability
27.9%8/10

Strong operational efficiency at 27.9%

Free Cash FlowQuality
$1.82B8/10

Generating 1.8B in free cash flow

IRWD6 strengths · Avg: 9.8/10
P/E RatioValuation
5.3x10/10

Attractively priced relative to earnings

Operating MarginProfitability
68.1%10/10

Strong operational efficiency at 68.1%

Revenue GrowthGrowth
158.9%10/10

Revenue surging 158.9% year-over-year

EPS GrowthGrowth
1047.0%10/10

Earnings expanding 1047.0% YoY

Debt/EquityHealth
-2.7510/10

Conservative balance sheet, low leverage

Profit MarginProfitability
28.3%9/10

Keeps 28 of every $100 in revenue as profit

Areas to Watch

AZN2 concerns · Avg: 3.0/10
P/E RatioValuation
27.5x4/10

Moderate valuation

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

IRWD3 concerns · Avg: 2.3/10
Market CapQuality
$544.87M3/10

Smaller company, higher risk/reward

Return on EquityProfitability
-575.0%2/10

ROE of -575.0% — below average capital efficiency

Altman Z-ScoreHealth
-4.212/10

Distress zone — elevated risk

Comparative Analysis Report

WallStSmart Research

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.2% and operating margin at 27.9%. Revenue growth of 12.5% demonstrates continued momentum.

Bull Case : IRWD

The strongest argument for IRWD centers on P/E Ratio, Operating Margin, Revenue Growth. Profitability is solid with margins at 28.3% and operating margin at 68.1%. Revenue growth of 158.9% demonstrates continued momentum.

Bear Case : AZN

The primary concerns for AZN are P/E Ratio, Altman Z-Score.

Bear Case : IRWD

The primary concerns for IRWD are Market Cap, Return on Equity, Altman Z-Score.

Key Dynamics to Monitor

AZN profiles as a mature stock while IRWD is a growth play — different risk/reward profiles.

IRWD carries more volatility with a beta of 0.24 — expect wider price swings.

IRWD is growing revenue faster at 158.9% — sustainability is the question.

AZN generates stronger free cash flow (1.8B), providing more financial flexibility.

Bottom Line

IRWD scores higher overall (69/100 vs 64/100), backed by strong 28.3% margins and 158.9% revenue growth. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

Ironwood Pharmaceuticals Inc

HEALTHCARE · DRUG MANUFACTURERS - SPECIALTY & GENERIC · USA

Ironwood Pharmaceuticals, Inc., a healthcare company, focuses on the development and commercialization of gastrointestinal (GI) products. The company is headquartered in Boston, Massachusetts.

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