WallStSmart

AstraZeneca PLC (AZN)vsInsmed Inc (INSM)

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Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 7275% more annual revenue ($60.44B vs $819.56M). AZN leads profitability with a 17.2% profit margin vs -144.4%. INSM appears more attractively valued with a PEG of 1.09. AZN earns a higher WallStSmart Score of 64/100 (C+).

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.0Profit: 8.5Value: 6.0Quality: 5.0
Piotroski: 6/9Altman Z: 1.48

INSM

Hold

39

out of 100

Grade: F

Growth: 8.0Profit: 2.0Value: 4.3Quality: 5.5
Piotroski: 4/9Altman Z: -3.96
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AZNUndervalued (+8.2%)

Margin of Safety

+8.2%

Fair Value

$194.77

Current Price

$185.95

$8.82 discount

UndervaluedFair: $194.77Overvalued
INSMSignificantly Overvalued (-16.6%)

Margin of Safety

-16.6%

Fair Value

$83.92

Current Price

$104.92

$21.00 premium

UndervaluedFair: $83.92Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$282.69B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
21.9%9/10

Every $100 of equity generates 22 in profit

Operating MarginProfitability
27.9%8/10

Strong operational efficiency at 27.9%

Free Cash FlowQuality
$1.82B8/10

Generating 1.8B in free cash flow

INSM1 strengths · Avg: 10.0/10
Revenue GrowthGrowth
229.6%10/10

Revenue surging 229.6% year-over-year

Areas to Watch

AZN2 concerns · Avg: 3.0/10
P/E RatioValuation
27.5x4/10

Moderate valuation

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

INSM4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Debt/EquityHealth
1.063/10

Elevated debt levels

Price/BookValuation
32.2x2/10

Trading at 32.2x book value

Return on EquityProfitability
-167.9%2/10

ROE of -167.9% — below average capital efficiency

Comparative Analysis Report

WallStSmart Research

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.2% and operating margin at 27.9%. Revenue growth of 12.5% demonstrates continued momentum.

Bull Case : INSM

The strongest argument for INSM centers on Revenue Growth. Revenue growth of 229.6% demonstrates continued momentum. PEG of 1.09 suggests the stock is reasonably priced for its growth.

Bear Case : AZN

The primary concerns for AZN are P/E Ratio, Altman Z-Score.

Bear Case : INSM

The primary concerns for INSM are EPS Growth, Debt/Equity, Price/Book.

Key Dynamics to Monitor

AZN profiles as a mature stock while INSM is a hypergrowth play — different risk/reward profiles.

INSM carries more volatility with a beta of 0.77 — expect wider price swings.

INSM is growing revenue faster at 229.6% — sustainability is the question.

AZN generates stronger free cash flow (1.8B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (64/100 vs 39/100), backed by strong 17.2% margins and 12.5% revenue growth. Both earn "Buy" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

Insmed Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Insmed Incorporated, a biopharmaceutical company, develops and markets therapies for patients with rare and serious diseases. The company is headquartered in Bridgewater, New Jersey.

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