WallStSmart

AstraZeneca PLC (AZN)vsCuris Inc (CRIS)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 855613% more annual revenue ($60.44B vs $7.06M). AZN leads profitability with a 17.2% profit margin vs -299.7%. AZN earns a higher WallStSmart Score of 64/100 (C+).

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.0Profit: 8.5Value: 6.0Quality: 5.0
Piotroski: 6/9Altman Z: 1.48

CRIS

Avoid

26

out of 100

Grade: F

Growth: 2.7Profit: 2.0Value: 4.0Quality: 5.5
Piotroski: 4/9Altman Z: -88.09
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AZNUndervalued (+8.2%)

Margin of Safety

+8.2%

Fair Value

$194.77

Current Price

$185.95

$8.82 discount

UndervaluedFair: $194.77Overvalued
CRISSignificantly Overvalued (-82.8%)

Margin of Safety

-82.8%

Fair Value

$0.58

Current Price

$0.47

$0.11 premium

UndervaluedFair: $0.58Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$282.69B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
21.9%9/10

Every $100 of equity generates 22 in profit

Operating MarginProfitability
27.9%8/10

Strong operational efficiency at 27.9%

Free Cash FlowQuality
$1.82B8/10

Generating 1.8B in free cash flow

CRIS2 strengths · Avg: 9.5/10
Price/BookValuation
0.7x10/10

Reasonable price relative to book value

Debt/EquityHealth
0.119/10

Conservative balance sheet, low leverage

Areas to Watch

AZN2 concerns · Avg: 3.0/10
P/E RatioValuation
27.5x4/10

Moderate valuation

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

CRIS4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$19.49M3/10

Smaller company, higher risk/reward

Return on EquityProfitability
-166.6%2/10

ROE of -166.6% — below average capital efficiency

Revenue GrowthGrowth
-66.0%2/10

Revenue declined 66.0%

Comparative Analysis Report

WallStSmart Research

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.2% and operating margin at 27.9%. Revenue growth of 12.5% demonstrates continued momentum.

Bull Case : CRIS

The strongest argument for CRIS centers on Price/Book, Debt/Equity.

Bear Case : AZN

The primary concerns for AZN are P/E Ratio, Altman Z-Score.

Bear Case : CRIS

The primary concerns for CRIS are EPS Growth, Market Cap, Return on Equity.

Key Dynamics to Monitor

AZN profiles as a mature stock while CRIS is a turnaround play — different risk/reward profiles.

CRIS carries more volatility with a beta of 3.06 — expect wider price swings.

AZN is growing revenue faster at 12.5% — sustainability is the question.

AZN generates stronger free cash flow (1.8B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (64/100 vs 26/100), backed by strong 17.2% margins and 12.5% revenue growth. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

Curis Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Curis, Inc., a biotechnology company, is dedicated to the discovery and development of drug candidates for the treatment of human cancers in the United States. The company is headquartered in Lexington, Massachusetts.

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