WallStSmart

AstraZeneca PLC (AZN)vsBioCryst Pharmaceuticals Inc (BCRX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 6724% more annual revenue ($60.44B vs $885.72M). AZN leads profitability with a 17.2% profit margin vs -51.7%. AZN appears more attractively valued with a PEG of 1.33. AZN earns a higher WallStSmart Score of 64/100 (C+).

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.0Profit: 8.5Value: 6.0Quality: 5.0
Piotroski: 6/9Altman Z: 1.48

BCRX

Avoid

31

out of 100

Grade: F

Growth: 6.7Profit: 4.0Value: 4.0Quality: 6.0
Piotroski: 5/9Altman Z: 0.31
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AZNUndervalued (+10.7%)

Margin of Safety

+10.7%

Fair Value

$193.96

Current Price

$172.48

$21.48 discount

UndervaluedFair: $193.96Overvalued

Intrinsic value data unavailable for BCRX.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$261.94B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
20.7%9/10

Every $100 of equity generates 21 in profit

Operating MarginProfitability
27.9%8/10

Strong operational efficiency at 27.9%

Free Cash FlowQuality
$2.13B8/10

Generating 2.1B in free cash flow

BCRX1 strengths · Avg: 10.0/10
Debt/EquityHealth
-1.5510/10

Conservative balance sheet, low leverage

Areas to Watch

AZN2 concerns · Avg: 3.0/10
P/E RatioValuation
25.4x4/10

Moderate valuation

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

BCRX4 concerns · Avg: 2.5/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

PEG RatioValuation
9.392/10

Expensive relative to growth rate

Return on EquityProfitability
-1925.0%2/10

ROE of -1925.0% — below average capital efficiency

Free Cash FlowQuality
$-62.54M2/10

Negative free cash flow — burning cash

Comparative Analysis Report

WallStSmart Research

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.2% and operating margin at 27.9%. Revenue growth of 12.5% demonstrates continued momentum.

Bull Case : BCRX

The strongest argument for BCRX centers on Debt/Equity.

Bear Case : AZN

The primary concerns for AZN are P/E Ratio, Altman Z-Score.

Bear Case : BCRX

The primary concerns for BCRX are EPS Growth, PEG Ratio, Return on Equity.

Key Dynamics to Monitor

AZN profiles as a mature stock while BCRX is a turnaround play — different risk/reward profiles.

BCRX carries more volatility with a beta of 0.54 — expect wider price swings.

AZN is growing revenue faster at 12.5% — sustainability is the question.

AZN generates stronger free cash flow (2.1B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (64/100 vs 31/100), backed by strong 17.2% margins and 12.5% revenue growth. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

BioCryst Pharmaceuticals Inc

HEALTHCARE · DRUG MANUFACTURERS - SPECIALTY & GENERIC · USA

BioCryst Pharmaceuticals, Inc., a biotechnology company, discovers oral and small molecule drugs. The company is headquartered in Durham, North Carolina.

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