WallStSmart

Apellis Pharmaceuticals Inc (APLS)vsargenx NV ADR (ARGX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

argenx NV ADR generates 329% more annual revenue ($4.74B vs $1.11B). ARGX leads profitability with a 31.4% profit margin vs 12.1%. APLS trades at a lower P/E of 38.3x. ARGX earns a higher WallStSmart Score of 73/100 (B).

APLS

Buy

50

out of 100

Grade: C-

Growth: 8.0Profit: 7.5Value: 6.3Quality: 5.5
Piotroski: 5/9Altman Z: -2.39

ARGX

Strong Buy

73

out of 100

Grade: B

Growth: 10.0Profit: 9.5Value: 6.7Quality: 8.5
Piotroski: 3/9Altman Z: 4.92
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

APLSUndervalued (+88.5%)

Margin of Safety

+88.5%

Fair Value

$194.37

Current Price

$41.03

$153.34 discount

UndervaluedFair: $194.37Overvalued
ARGXUndervalued (+62.4%)

Margin of Safety

+62.4%

Fair Value

$2217.64

Current Price

$891.32

$1326.32 discount

UndervaluedFair: $2217.64Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

APLS2 strengths · Avg: 10.0/10
Return on EquityProfitability
33.2%10/10

Every $100 of equity generates 33 in profit

Revenue GrowthGrowth
60.9%10/10

Revenue surging 60.9% year-over-year

ARGX6 strengths · Avg: 10.0/10
Profit MarginProfitability
31.4%10/10

Keeps 31 of every $100 in revenue as profit

Operating MarginProfitability
30.0%10/10

Strong operational efficiency at 30.0%

Revenue GrowthGrowth
62.6%10/10

Revenue surging 62.6% year-over-year

EPS GrowthGrowth
114.0%10/10

Earnings expanding 114.0% YoY

Debt/EquityHealth
0.0110/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
4.9210/10

Safe zone — low bankruptcy risk

Areas to Watch

APLS4 concerns · Avg: 3.8/10
P/E RatioValuation
38.3x4/10

Premium valuation, high expectations priced in

Price/BookValuation
12.7x4/10

Trading at 12.7x book value

EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Debt/EquityHealth
1.183/10

Elevated debt levels

ARGX3 concerns · Avg: 3.0/10
P/E RatioValuation
39.1x4/10

Premium valuation, high expectations priced in

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Price/BookValuation
188.4x2/10

Trading at 188.4x book value

Comparative Analysis Report

WallStSmart Research

Bull Case : APLS

The strongest argument for APLS centers on Return on Equity, Revenue Growth. Revenue growth of 60.9% demonstrates continued momentum.

Bull Case : ARGX

The strongest argument for ARGX centers on Profit Margin, Operating Margin, Revenue Growth. Profitability is solid with margins at 31.4% and operating margin at 30.0%. Revenue growth of 62.6% demonstrates continued momentum.

Bear Case : APLS

The primary concerns for APLS are P/E Ratio, Price/Book, EPS Growth.

Bear Case : ARGX

The primary concerns for ARGX are P/E Ratio, Piotroski F-Score, Price/Book.

Key Dynamics to Monitor

ARGX carries more volatility with a beta of -0.03 — expect wider price swings.

ARGX is growing revenue faster at 62.6% — sustainability is the question.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

ARGX scores higher overall (73/100 vs 50/100), backed by strong 31.4% margins and 62.6% revenue growth. APLS offers better value entry with a 88.5% margin of safety. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Apellis Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Apellis Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the development of therapeutic compounds through inhibition of the complement system for autoimmune and inflammatory diseases. The company is headquartered in Waltham, Massachusetts.

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argenx NV ADR

HEALTHCARE · BIOTECHNOLOGY · USA

argenx SE, a clinical-phase biotechnology company, focuses on the development of antibody-based therapies for the treatment of autoimmune diseases, hematology and cancer. The company is headquartered in Breda, the Netherlands.

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